BRAF/MEK rechallenge

This moderated forum is to support the needs of patients with stage IV melanoma, as well as to answer questions about treatment options and what to expect.

BRAF/MEK rechallenge

Postby Thomvdv » Thu Mar 09, 2017 9:27 am

In Dutch but important:
http://www.uzbrussel.be/u/view/nl/11084 ... erken.html

full LANCET paper downloadable if you click on "U kan de wetenschappelijke studie hier bekijken"

prof. Neyns (UZ Brussels - onc of my sister)


Trail for BRAF/MEK rechallenge after initial resistance kicked in. Most patients were out of treatment.

° 18 of 25 patients again had response!
° clear after 2 weeks if you have a rechallenge
° no grade 4_5 adverse events
° The median progression-free survival during rechallenge was 4,9 months
Thomvdv
 
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Re: BRAF/MEK rechallenge

Postby Catherine Poole » Thu Mar 09, 2017 11:57 am

Yes! Dr. Neyns is on our board and very dear to me as he took care of my Brussels sister Pati. It was our dear friend who we later lost that took the BRAF/mek as rechallenge on his own and came out of hospice. It is definitely worth a try. thanks for posting
Catherine M. Poole, President/Founder
Melanoma International Foundation
Catherine Poole
 
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Re: BRAF/MEK rechallenge

Postby Thomvdv » Fri Mar 10, 2017 4:37 am

ur welcome!
Thomvdv
 
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Re: BRAF/MEK rechallenge

Postby KoriRod » Mon Mar 20, 2017 5:13 pm

I tried to translate the page to English, but it looks like that is the only language not supported.

Does anyone have a translation?
KoriRod
 
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Re: BRAF/MEK rechallenge

Postby KoriRod » Mon Mar 20, 2017 5:15 pm

KoriRod wrote:I tried to translate the page to English, but it looks like that is the only language not supported.

Does anyone have a translation?

Never mind.

I was messing around with the page, and I found that you don't have to select a language. Just hit translate.

Hope that helps someone as technologically challenged as me.
KoriRod
 
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Joined: Fri Mar 10, 2017 7:15 pm


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