Thanks for your replies, Karen and Catherine.
The Zelboraf was still working, but the doctors wanted her to be able to get into the anti-PD1 trial while there are openings, since the drug seems so promising.
The study is: Study of MK-3475 in Participants With Progressive Locally Advanced or Metastatic Carcinoma, Melanoma, or Non-small Cell Lung Carcinoma (P07990/MK-3475-001 AM5)
In the beginning, her (previous) doctor assured her that he would keep a close watch on the progression of the tumors and recommend that she go back on the Zelboraf if things progressed too fast. He and the other doctors seem like they just have too many patients to keep an eye on my mom... she wasn't asked to report new tumors and they only do PET scans/blood work about once a month. She is now having severe digestive problems, so that she can hardly eat anything without it coming out one end or the other. I don't know if it is related to the cancer, as she has had digestive issues all of her life, just never this severe.
I wish that we knew how likely it would be that there would be another PD1 trial once the Zelboraf stops working. The only other treatment she has had was an electorporation vaccine trial which did not work... so ipi and vervoy seem to still be on the table as options. I really want her to start back on the Zelboraf, but she wants to hear that recommendation from a doctor. She goes back to SF in one week for bloodwork, then one more week before the 1st infusion... hopefully she will be able to eat/drink so that she will be able to make it