mek 116513 trial

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ronen
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mek 116513 trial

Post by ronen » Tue Feb 05, 2019 10:26 am

hi,
for the last 6 years (!) I was on mek 116513 (combi - v) trial.
originally by GSK, later by NOVARTIS.
(mekinist+ tafinlar vs. zelboraf).
now novartis ended the trial.
Anyone here from that trial?

Catherine Poole
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Re: mek 116513 trial

Post by Catherine Poole » Fri Feb 08, 2019 8:14 pm

How are you doing? What were your side effects like? Thanks for posting!
Catherine M. Poole, President/Founder
Melanoma International Foundation

Catherine Poole
Posts: 11230
Joined: Wed Jan 02, 2008 12:09 am

Re: mek 116513 trial

Post by Catherine Poole » Tue Feb 12, 2019 3:06 pm

Please tell us more
Catherine M. Poole, President/Founder
Melanoma International Foundation

chelseaclark
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Re: mek 116513 trial

Post by chelseaclark » Thu Jul 18, 2019 3:15 am

Genotoxicity, compared to other types of toxicity, may result in severe consequences that can be amplified and inherited after exceptionally long periods following exposure. Even DNA damage that occurs in a single cell caused by genotoxic drugs at low exposure can cause unexpected severe consequences in the long run.

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