Also, even though there are newer drugs on trial, that shouldn’t diminish the reasons why IPI was considered a major breakthrough, just a very few years ago.
In 2011 I was disappointed, like Jonathan, that I couldn’t get into a PD1 trial (disqualified because of brain metastases). But I believe now that getting IPI after neurosurgery and radiation — given that it’s a percentage play like every other melanoma treatment — is why I’ve been doing well and not had a follow-on recurrence for over 2 years now, knock on wood.
Maybe there was some kind of ‘priming’ by previous IL2 treatment (which cleared out my lungs completely in 2010), I’ll never know. And maybe my lungs are still clean because of the follow-on IPI treatment in 2011, I’ll never know that either.