I had no idea what had happened to Nick. I worked with him and tried appealing for Pd1 but he had meningeal disease which is really difficult to treat and I don’t know of any pharma giving it out in compassionate use. I am surprised they did allow him into the TIL regimen, but knowing his stamina I’m sure he insisted. Pati entered TIL therapy in much better condition than Nick and it really robbed her of her ability to fight further. It seems illogical and archaic to use such old methods, to get a good result. Melanoma clears up on its own in a small percentage, those without systemic treatment and I think it is the immune system suddenly recognizing the enemy. So I’m not sure we should weaken the body at all in this fight. Just my two cents.