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No ipilimumab is allowed

Exclusion Criteria:

Prior therapy with an immune cell modulating antibody except for anti-Cytotoxic T Lymphocyte Antigen 4 (CTLA4)

Active or chronic autoimmune diseases

Uncontrolled or significant cardiovascular disease

Chronic hepatitis

Active infection

Active Central nervous system (CNS) metastases”

Ipilimumab is anti cytotoxic T lymphocyte antigend 4(CTLA4) so that is excluded from the exclusions