Home Forums Melanoma Diagnosis: Stage IV A few openings in a phase I PD I trial

  • This topic is empty.
Viewing 5 posts - 1 through 5 (of 5 total)
  • Author
  • #20565
    Catherine Poole

    Please check here for possible openings. We don’t know much about this PD1, but it could be promising: http://clinicaltrials.gov/ct2/show/NCT01352884?term=nct+01352884&rank=1


    Thanks for posting this, Catherine. Is it my imagination, or does this trial seem to be less restrictive? The issues that stand in my way w/Merck & BMS are measurable disease, measurable disease on prior-irradiated skin, prior Remicade use (don’t remember if that one is BMS or Merck). This is SO frustrating!



    Catherine Poole

    It is less restrictive, because it is phase I, just figuring out dosage, no true idea of efficacy yet.


    This is my anti pd 1 trial-

    Phase I Study of Anti-PD-1 Human Monoclonal Antibody MDX-1106 (BMS-936558) and Vaccine Therapy Comprising gp100:209-217(210M) Peptide, MART-1:26-35(27L) Peptide, gp100:280-288(288V) Peptide, NY-ESO-1 Peptide, and Montanide ISA 51 VG in Patients With Resected Stage IV Melanoma


    There is NO concurrent use of steroids like Remicade…• At least 2 weeks since prior immunosuppressive doses of systemic medications, such as steroids or absorbed topical steroids (doses > 10 mg/day prednisone or equivalent)

    Anti PD 1 helps keep the bodys immune system in overdrive and would defeat the purpose. I know I had some rashy hive like thing on my hands for two months, probably unrelated to the trial, and the derm doc rx’ed steroids, but my oncologist ( Dr Weber) found out before I started to take it and said no way…the rash eventually healed without the use of it.


    Claritin helps me with the rash I get from the chemo meds I take.

Viewing 5 posts - 1 through 5 (of 5 total)
  • The forum ‘Melanoma Diagnosis: Stage IV’ is closed to new topics and replies.