I have stage IV melanoma with several abdominal mets, and am travelling to Memorial-Sloan-Kettering in NY to be part of this trial:
CA209-004, A Phase Ib, Open-Label, Multicenter Dose-Escalation Study of MDX-1106 (Nivolumab; BMS-936558) in Combination with Ipilimumab (BMS-734016) in Subjects with Unresectable Stage III or Stage IV Malignant Melanoma
I’ve received my first four doses (the ipi & nivo in combination), and am now going to get the nivolumab alone every two weeks.
I recently had my first scans, and there were no new mets, and an overall reduction in the existing lesions of 62%. (the largest was about 7 x 5 cm, and that’s shrunk by half).
The next scans will be in a few weeks. I’m on Prednisone now for some Ipi-induced colitis, but it’s ok.
Cautiously relieved and hopeful that others can also benefit from the explosion of research happening right now….