I am the last participant in this trial, EMR200066-006, for my oncologist. After 10 cycles (=30 weeks) I am still NED. This trial consists of:
A combination of two experimental drugs, MSC1936369B (Mitogen-activated protein extracellular signal-regulated kinase (Mek) Inhibitor) and SAR245409 (Phosphatidylinositol 3-kinase (Pi3K)/Mammalian Target of Rapamycin (mTOR) inhibitor).
I was pretty down after 20 weeks or so, but in reducing the dosage by 25%, everything got a lot better. Also, by taking these drugs at 11 PM, it makes for an easier night and day, since I usually have the most fatigue in the first 6 hours. After that, and the reduction in dosage, I felt good enough to return to work.
I did make the mistake (twice actually – ouch) of being in the indirect sun for more than a minute and getting a nice lobster rash/burn on my arms, which impressed all my friends.
Previously I recommended a book by John Green, “The Fault in Our Stars”, It is suppose to be released in 2014 as a movie. I suggest reading the book first.
My oncologist works at Pinnacle Oncology, in Scottsdale AZ.