Interesting research for BRAF Negative Folks Home › Forums › Melanoma Diagnosis: Stage IV › Interesting research for BRAF Negative Folks This topic is empty. Viewing 3 posts - 1 through 3 (of 3 total) Author Posts July 16, 2012 at 8:58 pm #20486 Catherine PooleKeymaster It seems they might respond to the MEK inhibitor, which we saw with one of our people here on the forum: http://www.eurekalert.org/pub_releases/2012-07/vumc-ubm071612.php July 17, 2012 at 2:25 am #55518 kylezParticipant 2 WT mutations that were found in my tumor samples are: BRAF G466E (from the original BRAF testing done by Kaiser) NRAS G12A (from testing done at UCSF). I’ve seen the NRAS one mentioned as a known mutation seen in other patients’ tumors, but so far not the G466 BRAF one. July 17, 2012 at 11:41 am #55519 Catherine PooleKeymaster I think this is all very interesting and exciting when we can match a mutation to a therapy! Author Posts Viewing 3 posts - 1 through 3 (of 3 total) The forum ‘Melanoma Diagnosis: Stage IV’ is closed to new topics and replies.