Home Forums Melanoma Diagnosis: Stage IV Ipi vs hIL-2

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    I just talked to Gary’s oncologist. He said that if Gary chooses the Ipi first then he can’t do the hIL-2 later if the Ipi doesn’t work. So if the Ipi doesn’t work is that it?? No other options???

    Catherine Poole

    IL2 has a 6% response rate, IPI/Yervoy has 20-30% percent and is far less toxic. Some do believe there is a synergy between the two drugs, but I don’t believe one has to preceed the other. Also, that synergy is not well proven. I would ask him what he is referring to. IL2 is often a last ditch because of the toxicity associated with it, requiring a stay in the ICU etc.



    I did IL-2 after Ipi. Then I did an ipi re-induction as well. As Catherine said, not sure what Gary’s doctor is referring to.

    all the best,


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