My pathology report still confuses me
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September 25, 2018 at 7:15 am #23399
Bella4444
ParticipantHiiiiiii again haha I just came across my pathology report and I want to write it in full and get an idea if this confuses anyone else…ok here it is in full.
MICROSCOPIC:
Skin sections show confluent proliferation of atypical melanocytes at the derm0-epidermal junction, singly and in nests.
There is upward migration of melanocytes into the epidermis but no evident ulceration. A few nests of atypical melanocytes also penetrate into the underlying dermis to Clark level 111 and measured depth of 0.75mm. The cells have a naevoid morphology and no definite mitoses are seen. Part of the lesion may be a pre existing naevus. The lesion is associated with a brisk lymphocytic infiltrate. There is no evidence of peri neural or vascular invasion. Excision of the lesion appears complete by a margin of 1.00mm from the insitu component, 3.6mm from the invasive component and 4.62mm from the deep margin.
Does any of this seem confusing or is this a normal sounding report??? This was from the first biopsy, I then obviously got the wle and was clear.
I’m confused about the insitu and invasive…..I’m confused about naevoid morphology and confluent proliferation….
Any insights?
Thank you x
September 25, 2018 at 12:50 pm #70709Catherine Poole
KeymasterThis appears to be a nevus, a mole, that showed no signs of mitosis, (growth) or characteristics of melanoma. I would not think this is anything to be concerned about. They use a lot of words that are confusing though! September 25, 2018 at 8:54 pm #70710Bella4444
ParticipantThanks Catherine This was my melanoma report…should I get someone else to look at it or is it too late now, or just forget it and be happy with the stage 1 diagnosis I was given?
September 26, 2018 at 12:33 am #70711Catherine Poole
KeymasterOk, it is confusing. Yes, I would get another opinion on the slides. You are close to the depth of SLNB but there was no mitosis. Did they discuss that? September 26, 2018 at 1:35 am #70712Bella4444
ParticipantThey said I didn’t need one as it was nothing more than a staging tool and as it was thin they thought the cons outweighed the pros… How do I go about getting someone else to look at the slides?
That’s what I thought if the melanoma had started growing vertically surely that would mean a mitocic rate would be given….it was a mole I had for as long as I can remember like childhood..
And can it have both an insitu component and invasive??? I have no idea why I’m looking into this a year later!
September 26, 2018 at 12:30 pm #70713Catherine Poole
KeymasterYes, it can have insitu and invasive both. But I would send the slides (ask the medical facility) to an expert. We think Martin Mihm is tops but it may be $300 out of pocket for his staff to review the slides. His contact is: Brigham and Women’s Hospital
Mihm Cutaneous Pathology Consultative Service
41 Avenue Louis Pasteur
Suite 320
Boston, MA 02115
Phone: (617) 264-3030
Fax: (617) 264-3013
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