Home Forums Melanoma Diagnosis: Stages I &II My pathology report still confuses me

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  • #23399
    Bella4444
    Participant

    Hiiiiiii again haha

    I just came across my pathology report and I want to write it in full and get an idea if this confuses anyone else…ok here it is in full.

    MICROSCOPIC:

    Skin sections show confluent proliferation of atypical melanocytes at the derm0-epidermal junction, singly and in nests.

    There is upward migration of melanocytes into the epidermis but no evident ulceration. A few nests of atypical melanocytes also penetrate into the underlying dermis to Clark level 111 and measured depth of 0.75mm. The cells have a naevoid morphology and no definite mitoses are seen. Part of the lesion may be a pre existing naevus. The lesion is associated with a brisk lymphocytic infiltrate. There is no evidence of peri neural or vascular invasion. Excision of the lesion appears complete by a margin of 1.00mm from the insitu component, 3.6mm from the invasive component and 4.62mm from the deep margin.

    Does any of this seem confusing or is this a normal sounding report??? This was from the first biopsy, I then obviously got the wle and was clear.

    I’m confused about the insitu and invasive…..I’m confused about naevoid morphology and confluent proliferation….

    Any insights?

    Thank you x

    #70709
    Catherine Poole
    Keymaster

    This appears to be a nevus, a mole, that showed no signs of mitosis, (growth) or characteristics of melanoma. I would not think this is anything to be concerned about. They use a lot of words that are confusing though!

    #70710
    Bella4444
    Participant

    Thanks Catherine

    This was my melanoma report…should I get someone else to look at it or is it too late now, or just forget it and be happy with the stage 1 diagnosis I was given?

    #70711
    Catherine Poole
    Keymaster

    Ok, it is confusing. Yes, I would get another opinion on the slides. You are close to the depth of SLNB but there was no mitosis. Did they discuss that?

    #70712
    Bella4444
    Participant

    They said I didn’t need one as it was nothing more than a staging tool and as it was thin they thought the cons outweighed the pros…

    How do I go about getting someone else to look at the slides?

    That’s what I thought if the melanoma had started growing vertically surely that would mean a mitocic rate would be given….it was a mole I had for as long as I can remember like childhood..

    And can it have both an insitu component and invasive??? I have no idea why I’m looking into this a year later!

    #70713
    Catherine Poole
    Keymaster

    Yes, it can have insitu and invasive both. But I would send the slides (ask the medical facility) to an expert. We think Martin Mihm is tops but it may be $300 out of pocket for his staff to review the slides. His contact is:

    Brigham and Women’s Hospital

    Mihm Cutaneous Pathology Consultative Service

    41 Avenue Louis Pasteur

    Suite 320

    Boston, MA 02115

    Phone: (617) 264-3030

    Fax: (617) 264-3013

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