Home Forums Melanoma Diagnosis: Stages I &II My pathology report still confuses me

  • This topic is empty.
Viewing 6 posts - 1 through 6 (of 6 total)
  • Author
  • #23399

    Hiiiiiii again haha

    I just came across my pathology report and I want to write it in full and get an idea if this confuses anyone else…ok here it is in full.


    Skin sections show confluent proliferation of atypical melanocytes at the derm0-epidermal junction, singly and in nests.

    There is upward migration of melanocytes into the epidermis but no evident ulceration. A few nests of atypical melanocytes also penetrate into the underlying dermis to Clark level 111 and measured depth of 0.75mm. The cells have a naevoid morphology and no definite mitoses are seen. Part of the lesion may be a pre existing naevus. The lesion is associated with a brisk lymphocytic infiltrate. There is no evidence of peri neural or vascular invasion. Excision of the lesion appears complete by a margin of 1.00mm from the insitu component, 3.6mm from the invasive component and 4.62mm from the deep margin.

    Does any of this seem confusing or is this a normal sounding report??? This was from the first biopsy, I then obviously got the wle and was clear.

    I’m confused about the insitu and invasive…..I’m confused about naevoid morphology and confluent proliferation….

    Any insights?

    Thank you x

    Catherine Poole

    This appears to be a nevus, a mole, that showed no signs of mitosis, (growth) or characteristics of melanoma. I would not think this is anything to be concerned about. They use a lot of words that are confusing though!


    Thanks Catherine

    This was my melanoma report…should I get someone else to look at it or is it too late now, or just forget it and be happy with the stage 1 diagnosis I was given?

    Catherine Poole

    Ok, it is confusing. Yes, I would get another opinion on the slides. You are close to the depth of SLNB but there was no mitosis. Did they discuss that?


    They said I didn’t need one as it was nothing more than a staging tool and as it was thin they thought the cons outweighed the pros…

    How do I go about getting someone else to look at the slides?

    That’s what I thought if the melanoma had started growing vertically surely that would mean a mitocic rate would be given….it was a mole I had for as long as I can remember like childhood..

    And can it have both an insitu component and invasive??? I have no idea why I’m looking into this a year later!

    Catherine Poole

    Yes, it can have insitu and invasive both. But I would send the slides (ask the medical facility) to an expert. We think Martin Mihm is tops but it may be $300 out of pocket for his staff to review the slides. His contact is:

    Brigham and Women’s Hospital

    Mihm Cutaneous Pathology Consultative Service

    41 Avenue Louis Pasteur

    Suite 320

    Boston, MA 02115

    Phone: (617) 264-3030

    Fax: (617) 264-3013

Viewing 6 posts - 1 through 6 (of 6 total)
  • The forum ‘Melanoma Diagnosis: Stages I &II’ is closed to new topics and replies.