Home Forums Melanoma: Newly Diagnosed – Stages I & II new diagnosed stage 2

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  • #21043
    dbartlett
    Participant

    Hi all looking for any additional info on my path report as follows

    Superficial spreading malignant melanoma

    Breslow .7mm

    Clarke level 3

    Ulceration not identified

    Regression present

    Mitotic rate 12 mm2

    Lymphatic/perineural/angui/invasion not identified

    Tumor infiltrating lymphocytes brisk

    Deep margin not involved

    Peripheral margin involved

    Meeting with surgical oncologist next wed for consult needs wide excision located on upper abdomen

    As well as melanoma in duty on lower back and 2 dysplastic Nevis with dysplasia lower back and mid back

    Could use some help ok what all this means

    Any questions I should be asking. Derm said possible lymp biopsy.

    #59310
    chas66
    Participant

    An important question is, was the skin broken or bleeding above the mole before you had the biopsy. That’s what’s called the ulceration. Let us know. A high mitotic rate (which is what you have-how fast the cancer cells divide) with the low Breslow (depth of the cancer) is something to be concerned with.

    #59311
    Catherine Poole
    Keymaster

    We usually suggest you get another opinion on your pathology by an expert. Where was yours done? Your melanoma is fairly shallow depth at .7 but the regression and mitotic rate can boost your risk. Are they suggesting you have a sentinel node biopsy? If the second opinion from an expert is the same, I would think of opting for a sentinel node biopsy. You can read more about that on this website (and be sure to look above in BLUE at the Newly Diagnosed area and Melanoma Terms. For more on the SLNb: http://www.melanomainternational.org/melanoma_info/sentinel_node_biopsy.html. I had a .76 depth melanoma with 1 mitotic and regression too, 24 years ago. Try not to worry and make sure you educate yourself and see the best expert if possible.

    #59312
    dbartlett
    Participant

    No it did not bleed at the time that I ever noticed. And it looks like it was not reported in the pathology or it was and its listed as stated above

    As far as the slb I am meeting with a oncology next week so far my Derm said it was small chance of doing one. Just wanted some advise from others who have been where I am now. So far the pathology came out of a lab in Ohio. My other question is there any worry over the 2 spots that they found. And would guess I’d they biopsy the others they mapped there is probably more but they are small in comparison to the one we are talking about.

    Thanks for the reply and kind words

    #59313
    krissy424
    Participant

    I would have the lymph node biopsy with the wide excision based on regression and the mitotic rate. Breslow.7 is a good number.

    Mine was Breslow .55 and Clark ll. Keep in touch.

    #59314
    cohanja
    Participant

    “Regression present” I’d ask if it was extensive regression (> 75%) or partial/focal regression.

    #59315
    Catherine Poole
    Keymaster

    Be sure to get a second opinion on the pathology. A high mitotic rate doesn’t often go hand in hand with a shallow lesion of .7. Your slides can easily be sent to an expert at a teaching institute. Or you can try: http://www.drmihm.com and have an opinion from Dr. Mihm, a Harvard expert. You want to be sure before you proceed with a SLNB that it is necessary. Regression can be a weakly negative factor. Mitotic factor means cells were dividing and reproducing at a certain rate.

    #59316
    chas66
    Participant

    That’s good that the skin wasn’t broken or bleeding, where your report says Ulceration- Not Identified, clearly state when you get the second opinion how the skin above was so they know it was not ulcerated, since ulceration effects staging. The cancer center that I went to for a review of my slides did change some of the numbers from the initial path report, so don’t be surprised if you see some of the data change. The Breslow depth works in your favor. Good luck, let us know how it works out.

    #59317
    dbartlett
    Participant

    Thanks for all the advise it is helpfull, I have been trying to gather as much insite as I can prior to wed visit with the surgical oncologist Dr. Adam Riker at advocate in tinly park Illinois. (any body have any feedback on him would be helpfull as well). I’ll ne sure to update after Wedwhen o know more seems like things are favorable but with some not normal results. Ie mitosos rate

    Thanks again for all your input

    #59318
    Worrywart
    Participant

    Hi there,

    Your Breslow is fairly low risk, but due to the regression and mitotic rate I’d push for the SNB. Your tumor infiltrating lymphocytes were brisk which indicates your body was aggressively attacking this lesion – that is good, but probably contributed to the regression. The only bad thing about regression is that sometimes it indicates your lesion could be deeper than what the path report states. Regression basically means yoru body was ‘eating’ it. Your deep margin was not involved, which is good. Your peripheral was involved, so there may still be some cancer cells left on your skin. This is fairly common with melanoma however. By “melanoma in duty” do you mean melanoma in situ? I have no idea what in-duty is?? Approx 8% of the melanoma population has more than one melanoma. You should consider mole mapping/photography to track your moles for change and new growth. A second opinion on pathology is usually covered by insurance and I consider it VERY important with any cancer diagnosis! Good luck at your appt!

    #59319
    dbartlett
    Participant

    Thanks for the input and yes in situ it should have read auto correct that i missed. This all came about from my first Derm visit to have a lump under a mole on side of my neck checked. Just a sist they said and had them check me out. I do have many moles and all the other negativefair skin green eyes red blnd hair ect. Thanks again for all the input

    #59320
    krissy424
    Participant

    It’s good that the path report

    stated No Ulceration. Just to clarify a point, my SSM had a bleeding gouge near the top

    of the lesion. It was from my fingernail. I had No Ulceration and was told

    that was something seen in the lab with microscope, not with the naked eye.

    #59321
    Worrywart
    Participant

    Did they biopsy that lump under a mole to confirm it was a cyst?

    #59322
    dbartlett
    Participant

    No they did not do biopsy. Quick look and said cyst and my choice to have it removed or not thinking I will have them take it off now and sent in for piece of mind

    #59323
    dbartlett
    Participant

    Just a update I had my wle and slnb yesterday all went well 2 nodes removed in left arm and 1 on right side. Now just the waiting game again to get the pathology back. Thanks to all for your input on this it has been helpful.

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