Home Forums Melanoma Diagnosis: Stage IV Progression on PD1? Here is a new option

  • This topic is empty.
Viewing 8 posts - 1 through 8 (of 8 total)
  • Author
    Posts
  • #22574
    Catherine Poole
    Keymaster

    https://clinicaltrials.gov/ct2/show/study/NCT02009449

    IL10 and Pd1 combination, reporting favorably, yet early

    #67498
    Gilly
    Participant

    does this mean you can effectively get a rechallenge of Pembro ??

    #67499
    Catherine Poole
    Keymaster

    Yes, that is how it appears. It is less toxic than the combo of IPI and Opdivo as well I am told. It also seems to be at some good melanoma centers which usually is a good sign.

    #67500
    Catherine Poole
    Keymaster

    The study on this was presented at ASCO, I have the slides, but too large to put here. Mostly has just been through the toxicity check and fared pretty well. (it isn’t IL2!)

    #67501
    Gilly
    Participant

    Thanks Catherine , is this the Sun et al paper ?

    #67502
    Catherine Poole
    Keymaster

    The presentation was by our scientific board member, Jeff Infante from Sarah Cannon Research Institute.

    #67503
    artiev
    Participant

    Thought some might like to know these daily injections do not mean having to move to where the trial is. Yes I’m naive. That’s what I thought when I first read it. I talked to the nurse and they teach you how to give yourself your own daily shot of il10. She explained its like people giving themself an insulin shot. The keytruda of course is the normal in the clinic iv. Sounded like it is up and running but the place I called has no patients yet and she was not aware of how it is doing at other locations.

    #67504
    Catherine Poole
    Keymaster

    Thanks Artie, you aren’t naive at all! I would have thought that as well. I imagine you have to call nearby centers to see what is up and running. I hope it works out for you as a plan. Thanks for letting us know this information, very helpful.

Viewing 8 posts - 1 through 8 (of 8 total)
  • The forum ‘Melanoma Diagnosis: Stage IV’ is closed to new topics and replies.