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February 6, 2013 at 1:17 pm #20999
I’ve heard it stated that thin melanomas aren’t deep enough to have reached blood vessels. . so, for instance, a melanoma that superficially invades into the papillary dermis. . .but if the papillary dermis supplies the epidermis with blood, how can that be true?February 6, 2013 at 3:13 pm #58995Catherine PooleKeymaster I am confused by your question. If a melanoma is shallow, it does not extend into the dermis, but only the epidermis and therefore does not have access to lymphatic or blood vessels. Yes, there are blood and lyphatic vessels in the dermis.February 6, 2013 at 4:17 pm #58996 Well, only in-situ doesn’t extend into the dermis. Everything else does. But, for those with thin invasive lesions, less than 0.75 or less than 0.50, etc…. that invade only into the superficial papillary dermis. . . I’ve had some doctors say that isn’t deep enough yet to have reached blood vessels. . so my question is how deep into the dermis are the blood vessels, 1 mm?February 9, 2013 at 1:55 am #58997WorrywartParticipant If it reaches blood vessels then it is usually stated in path report (if seen).February 9, 2013 at 12:56 pm #58998 so you pretty much know up front if it has spread via blood vessels? if not on path report, it hasn’t?
do they know how deep into the dermis are the blood vessels located?February 9, 2013 at 3:56 pm #58999TreeFrogParticipant
My layperson’s understanding of the matter is: for there to be vascular invasion (which would be noted on the path. report), there has to be something to invade. Blood vessels, even the smallest capillaries, don’t quite get to the epidermis or the outer part of the dermis (papillary dermis). An in situ or Stage 1 Clark’s II is not at a level where a blood vessel could penetrate it.
You know when you get a little scrape and it oozes clear liquid, but not blood? That’s what your body is providing to the outer layers of the dermis. I don’t know the exact medical terminology, but I believe it’s plasma that perfuses from the deeper capillaries upwards to the papillary dermis. Cells themselves cannot be exchanged via this perfusion.
That is why an in situ is considered to be cured by excision, and a Stage 1 very likely to be cured. The only exceptions would be if a pathologist got the staging wrong.
That’s how I understand it, anyway! Interesting question.
Stage 1 .47mm removed 2011.February 9, 2013 at 4:11 pm #59000
although doesn’t seem like you have to cut/scrape yourself very deep to get blood. . even the thinnest/slightest little cut usually generated bleedingFebruary 11, 2013 at 12:23 am #59001WorrywartParticipant
You don’t have to cut yourself deeply to get to blood. But 1 mm is very small…and less than 1 mm is even smaller. I don’t remember your exact stats but I know yours was smaller than 1mm.March 9, 2013 at 7:38 am #59002steve659Participant Some superficial cyst when appear in the blood vessels it means there is special kind of the disease of the dermatology and for this very soon treatment taken other wise any chronic disease appear in this regard for the patient.March 11, 2013 at 1:26 am #59003krissy424Participant Steve,
Buddy. Where are you from ? Your use of the English language makes you difficult to understand. I know it’s not April 1st. but after reading all of your posts, I get an April 1st kind of feeling .March 11, 2013 at 6:23 pm #59004wpatterson4Participant
“I get an April 1st kind of feeling”
The plot thickens…….
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