Hi,
I had regional radiotherapy while on full dose of Zelboraf. Although radiation dose was not very high (8 Gr) three days later severe radiodermatitis and burns were developed. Apparently, it was due to Zelboraf (something called re-call syndrome, if I remember correctly). It was painful, itchy and looked bad during first week or two, but nothing serious happened and I treated it just with moisturizers. Burns are still visible, but it looks much better now.
I guess radiotherapy worked, I can walk again!
Hope it will help,
Biljana